Phoenix, AZ – Injury Multi‑Vehicle Crash with Overturned Car at US‑101 & 46th St

Phoenix, AZ (October 7, 2025) – Multiple people were injured on October 7 after a crash involving several vehicles on US‑101 Northbound near 46th Street. One of the vehicles overturned during the collision, prompting an emergency response.

Phoenix Metro Area Fire crews arrived on the scene in the evening following reports of the crash. Authorities confirmed that the incident involved at least three vehicles, with one ending up on its roof in the number three lane. The exact cause of the accident remains under investigation.

Paramedics treated and transported victims to nearby hospitals. Details about the severity of injuries have not been released. Officials closed portions of the northbound freeway for several hours to clear the wreckage and conduct their investigation. Traffic was reopened later in the night.

Phoenix police continue to investigate to determine what led to the crash. The circumstances, including whether speed, distracted driving, or impairment played a role, have not been confirmed.

We wish a full and safe recovery to those injured in this incident and send support to all affected by this collision.

Multi‑Vehicle Crashes in Phoenix

Multi‑vehicle accidents are a significant safety concern on Arizona’s roadways, especially in urban areas such as Phoenix. These crashes often involve complex dynamics, including sudden stops, lane changes, or poor visibility conditions. Freeways like US‑101 carry heavy traffic at high speeds, increasing the potential severity of collisions.

Common causes of multi‑vehicle crashes include distracted driving, speeding, tailgating, and unsafe lane changes. Weather conditions and road maintenance issues can also play a role. In freeway settings, a single error by one driver can quickly cascade into a chain‑reaction collision, as vehicles have limited time and space to react.

Injuries from these accidents range widely, from minor scrapes to serious trauma. Overturned vehicles in such crashes present additional hazards, increasing the likelihood of severe injuries due to the violent forces involved. Victims may face long hospital stays, costly treatments, and prolonged recovery.

If a crash is caused by negligence or recklessness, victims may be entitled to compensation for medical expenses, lost wages, pain and suffering, and more. Navigating such claims can be complex, especially in multi‑vehicle collisions involving multiple insurance companies. An experienced Phoenix car accident lawyer can help victims gather evidence, deal with insurers, and build a case for fair compensation.

At National Injury Help, we support crash victims and their families during recovery. Our attorneys handle complex cases involving multiple vehicles and insurance disputes. We’ll gather evidence, investigate thoroughly, and help you pursue the compensation you deserve.

If you or a loved one has been injured in a multi‑vehicle accident in Phoenix, you are not alone. Please call our team at (866) 932‑4817 for a free consultation with National Injury Help.